Read This Before You Take Another Supplement

By The Wellness Guide

Here's what no one's telling you about the supplement industrial complex: that beautifully curated cabinet of trending pills might be the most expensive way to stay unwell.

We're watching men and women pop 15+ supplements daily—adaptogenic this, bioavailable that—without knowing a single baseline number. It's wellness theatre. And it's keeping you stuck in a cycle of expensive guesswork that's more likely to create imbalances than fix them.

Thanks for reading The Wellness’s Substack! Subscribe for free to receive new posts and support my work.

The people who are actually thriving? They're not following supplement influencers. They're following their bloodwork.

Let's call this what it is: biochemical bypassing.

Taking supplements without testing is like adjusting your thermostat whilst blindfolded. You might get lucky. But you're more likely to create new problems whilst masking the original ones.

The real biohackers aren't stacking—they're strategising. And it starts with three numbers most of your favourite wellness accounts have never mentioned.

The Trinity Nobody's Testing (But Should Be)

→ Vitamin D, Your Master Hormone Disguised as a Vitamin

This isn't just about immunity. Vitamin D is literally a hormone precursor that influences:

  • Testosterone and oestrogen production

  • Serotonin synthesis (hello, mood)

  • Insulin sensitivity

  • Bone density

  • Thyroid function

Yet 57% of UK adults are deficient. And here's the kicker: supplementing blindly can suppress your body's ability to activate it properly. Too much, and you're calcifying arteries. Too little, and you're running on 30% capacity.

The sweet spot: 40-60 ng/ml (100-150 nmol/L)

→ Vitamin K2, The Director Your Body Desperately Needs

Whilst everyone's obsessing over collagen supplements, they're missing the conductor of the entire mineralisation orchestra. K2 tells calcium where to go—into bones, not arteries. Without it, all that vitamin D you're taking? It's potentially creating cardiovascular chaos.

K2 deficiency symptoms masquerade as:

  • Chronic fatigue

  • Easy bruising

  • Dental issues

  • Osteoporosis

  • Heart disease

And guess what depletes it? The very "clean eating" everyone's promoting—low-fat diets, avoiding fermented foods, overcooked vegetables.

→ Choline, The Cognitive Currency You're Spending Without Earning

Your liver makes some. But not enough. Especially if you're:

  • Plant-based (eggs are the richest source)

  • On hormonal birth control

  • Stressed (who isn't?)

  • Drinking alcohol regularly

Low choline doesn't announce itself loudly. It whispers through:

  • Brain fog that coffee can't fix

  • Fatty liver (even if you don't drink)

  • Memory issues

  • Muscle weakness

  • Mood swings

The average UK woman gets 270mg daily. She needs 425-550mg. That gap? It's costing you more than any adaptogen could repay.

Why Your Trending Stack Is Making Things Worse

The Competitive Inhibition Nobody Mentions

Those 15 supplements you're taking with breakfast? They're competing for the same absorption pathways. Iron blocks zinc. Zinc blocks copper. Calcium blocks magnesium. You're creating nutritional traffic jams that leave you more depleted than when you started.

The Methylation Mess

Taking high-dose B vitamins without knowing your methylation status is like pouring petrol on a fire you can't see. Over-methylators taking methyl-B12? Hello, anxiety and insomnia. Under-methylators avoiding it? Welcome to chronic fatigue city.

The Stress Response Paradox

Adaptogens are meant to help with stress. But taking them without addressing basic nutritional deficiencies is like putting premium fuel in a car with no oil. Your body needs foundational nutrients to even process these compounds. Without them, you're just expensive urine.


The Real Wellness Protocol: Test, Don't Guess

Step 1: Get These Numbers

  • Vitamin D (25-hydroxy)

  • Active B12 (not just serum)

  • Ferritin (not just iron)

  • Full thyroid panel

  • Homocysteine

  • HbA1c

  • Inflammatory markers (CRP, ESR)

Step 2: Address Foundations First Before you add another adaptogen:

  • Is your vitamin D optimised?

  • Are you getting K2 from food or quality supplements?

  • Is your choline intake adequate?

  • Have you fixed your sleep?

  • Is your blood sugar stable?

Step 3: Supplement Strategically Only add what testing reveals you need. And always:

  • Take fat-soluble vitamins (D, K2, E, A) with fats

  • Space out competing minerals

  • Consider cofactors (D needs magnesium, B12 needs folate)

  • Retest in 3-6 months


The Truth About "Wellness Influencer" Protocols

That morning routine with 12 supplements before 9am? It's not optimisation—it's oxidation. Creating more stress than it solves.

People who are genuinely thriving understand this. Your body is infinitely smarter than any supplement stack. It just needs the right raw materials in the right ratios. Not more. Not trending. Just right.

The real glow-up isn't in what you add—it's in what you align.

Your body's asking for precision, not performance. Listen to it. Test for it. Then, and only then, supplement for it.

Because the most expensive supplement routine is the one that doesn't work. And the most effective? It's the one designed specifically for your biochemistry—not your Instagram feed.

Thanks for reading The Wellness’s Substack! Subscribe for free to receive new posts and support my work.

Chat with us