DoNotAge Pure NMN is a nicotinamide mononucleotide supplement in powder form, supplied as a bulk 100g jar.
£100
DoNotAge Pure NMN is a nicotinamide mononucleotide supplement in powder form, supplied as a bulk 100g jar.
DoNotAge Pure NMN is a nicotinamide mononucleotide supplement in powder form, supplied as a bulk 100g jar.
Follow the dosage guidance on the packaging, as appropriate amounts vary by individual and clinical context. Many people take NMN powder dissolved in water, typically in the morning. If you are working with a clinician, discuss your target dose before starting.
DoNotAge Pure NMN is a nicotinamide mononucleotide supplement in powder form, supplied as a bulk 100g jar. NMN is a direct precursor to NAD+ (nicotinamide adenine dinucleotide), a coenzyme present in every cell and central to energy metabolism, DNA repair, and the activity of sirtuins - a family of proteins studied for their role in cellular ageing. NAD+ levels decline measurably with age, and NMN supplementation is one of the more researched approaches to supporting those levels from the inside.
This product suits people who are actively monitoring their healthspan - typically those who have noted fatigue, reduced recovery, or age-related performance changes and want to address cellular energy at the root. It also fits well alongside regular blood testing, where baseline and follow-up panels can give some objective context to how the body is responding.
The powder format offers flexibility: doses can be adjusted more easily than with fixed capsules, which is useful when working with a clinician to find an appropriate amount. DoNotAge positions itself squarely in the longevity research space and is a recognised name among those following the NAD+ precursor literature closely. As with any supplement targeting a specific biochemical pathway, it is worth discussing with a GP or functional medicine doctor - particularly if you take medications that involve DNA-repair pathways or have a personal or family history of hormone-sensitive conditions.
Standard UK delivery included on every order, 1 to 3 working days after dispatch.
Next working day for £25 when you order by 12pm. Orders placed before 12pm on a working day leave the same day. Later orders leave the next working day.
You can return unopened and unused items within 30 days of delivery. This does not affect your statutory rights. Read the delivery and returns terms
Your Profile
Your first order creates it. Add your blood results or a wearable, and a doctor can recommend what suits you.
Sign inNMN (nicotinamide mononucleotide) is a precursor to NAD+, a coenzyme that declines with age and is essential for energy production, DNA repair, and sirtuin function. Supplementing with NMN is studied as a way to support the body's NAD+ levels, which fall significantly from around the fourth decade of life.
The active compound is the same. Powder allows more precise dose adjustments, which can be useful if you are working with a practitioner to find your optimal amount. Capsules offer more convenience and a fixed dose. Neither format is universally superior — it depends on how you want to use it.
NMN is generally considered well-tolerated, but it interacts with cellular pathways involved in DNA repair and energy metabolism. If you take prescription medications — particularly those affecting NAD+ metabolism, chemotherapy agents, or blood-sugar regulation — consult your GP before starting.
NAD+ pathway effects are not typically felt immediately. Some people report improvements in energy or recovery within a few weeks; for others the benefits are more subtle and best assessed through objective markers such as blood panels or monitored performance metrics over several months.
Those who are pregnant or breastfeeding should avoid NMN supplementation due to insufficient safety data. People with a personal or family history of hormone-sensitive conditions, or who are undergoing cancer treatment, should discuss it with their doctor before use. Check the packaging for any additional contraindications listed by the manufacturer.
Overall
6 months ago
Been taking this for about six weeks now, roughly 500mg in the morning mixed into water. The afternoon slump I'd had for years has genuinely reduced — not disappeared entirely, but much less pronounced. I was sceptical going in, so I'm pleasantly surprised. Powder dissolves easily and I barely taste it. Will keep going and plan to retest my NAD+ markers in a few months.
6 months ago
Switched from capsules because the cost per gram was getting silly. 100g lasts me a good while at my current dose and I appreciate being able to dial it up or down. No taste to speak of, which suits me fine. My functional medicine doctor was the one who suggested NMN and she approved of this brand specifically.
6 months ago
Take it alongside resveratrol and a B-complex. Hard to isolate what's doing what, honestly, but my sleep quality and recovery after sessions at the gym have both improved since I added NMN to the mix. I'm 47 and started noticing a real shift in how quickly I bounced back from exercise — this feels like part of that.
7 months ago
Really happy with how I've been feeling on this — more consistent energy and my brain fog seems lighter. Only gripe is the included scoop is quite flimsy and the markings wore off after about a week of use, so I ended up having to weigh it out with a kitchen scale instead. Minor in the grand scheme of things but worth mentioning.
7 months ago
Bought on a friend's recommendation. Solid product, mixes well, no complaints.
8 months ago
Started this before a half marathon training block after reading about NAD+ and cellular energy. Whether it's placebo or not, my recovery has felt noticeably quicker — I'm not as sore the day after long runs. Three months in and I've just reordered.
Biomarker check, £350MaryleboneSee your vitamin D, iron and B12.At our clinic in Marylebone, London, doctors also offer longevity medicine and private MRI scans.
A curated selection of products, tools and rituals, chosen by our doctors.
