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DGL is a form of liquorice root with the glycyrrhizin removed, which means it retains its soothing properties without the blood-pressure concerns associated with whole liquorice extract.
£40
DGL is a form of liquorice root with the glycyrrhizin removed, which means it retains its soothing properties without the blood-pressure concerns associated with whole liquorice extract.
DGL is a form of liquorice root with the glycyrrhizin removed, which means it retains its soothing properties without the blood-pressure concerns associated with whole liquorice extract.
Mix one scoop into water or a cool drink twice daily. Follow the dosage guidance on the packaging for any adjustments based on body weight or clinical context. Taking it with or just before meals is a common approach for gut-lining support formulas of this type.
EnteroMend by Thorne is a powdered gut-lining support formula combining three well-studied ingredients: L-glutamine, zinc carnosine, and deglycyrrhizinated liquorice (DGL). Each plays a distinct role. L-glutamine is the primary fuel source for enterocytes - the cells that line the intestinal wall - and is commonly used to support mucosal integrity during periods of stress, illness, or intense training. Zinc carnosine is a chelated compound studied specifically for its ability to adhere to the gastric and intestinal mucosa, where it may help stabilise the gut lining and reduce irritation. DGL is a form of liquorice root with the glycyrrhizin removed, which means it retains its soothing properties without the blood-pressure concerns associated with whole liquorice extract.
This combination suits people dealing with digestive discomfort, those recovering from a course of antibiotics or gut-disrupting medication, athletes in heavy training who experience gastrointestinal symptoms, or anyone whose blood work or clinical assessment points to compromised gut integrity. It fits neatly into a morning and evening routine alongside meals. Thorne is a brand with a strong track record in professional and clinical settings, and their manufacturing standards are consistently cited by practitioners who work with patients on targeted supplementation protocols.
Standard UK delivery included on every order, 1 to 3 working days after dispatch.
Next working day for £25 when you order by 12pm. Orders placed before 12pm on a working day leave the same day. Later orders leave the next working day.
You can return unopened and unused items within 30 days of delivery. This does not affect your statutory rights. Read the delivery and returns terms
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Sign inIt suits people with diagnosed or suspected gut lining compromise — for example, those with ongoing digestive discomfort, recovering from antibiotics or NSAIDs, or athletes experiencing GI distress during training. It is worth discussing with a clinician if you are managing a diagnosed condition such as IBD or IBS.
DGL (deglycyrrhizinated liquorice) has had the glycyrrhizin compound removed — this is the constituent linked to blood pressure elevation and hormonal effects. Most people who cannot tolerate whole liquorice extract tolerate DGL well, but if you have a known allergy to liquorice root, check with your doctor first.
L-glutamine and DGL are generally well tolerated alongside most supplements. Zinc can interfere with the absorption of certain antibiotics and copper, so if you are taking prescription medications or high-dose minerals, check with a pharmacist or clinician before adding this.
Gut lining support typically requires consistent use over several weeks. Most practitioners suggest a minimum of four to eight weeks before assessing response, though some people notice reduced bloating or discomfort sooner. Individual results vary depending on the underlying cause of symptoms.
It is generally advisable to mix gut-lining powders into cool or room-temperature liquids rather than hot drinks, as heat can degrade some amino acids. Check the packaging for any specific preparation guidance from Thorne.
Overall
6 months ago
Been struggling with gut issues for about two years after a brutal course of antibiotics. A friend who sees a functional medicine doctor recommended this and I've been taking it for six weeks now — one scoop in the morning, one before bed. The bloating has noticeably settled and I feel much more comfortable after meals. Would definitely reorder.
6 months ago
My nutritionist recommended this during a period of heavy marathon training. I was getting a lot of GI issues mid-run and it's made a real difference. Takes a few weeks to kick in but worth sticking with.
6 months ago
Noticed a genuine improvement in my digestive comfort after about three weeks. The issue is that at two scoops a day you go through this quite quickly, and at £37.99 a tub it adds up. Results are good though — I'll keep buying it, just wish it was better value for the number of servings.
6 months ago
Recommended by my gastroenterologist. I was sceptical about powders but this dissolved easily and didn't taste awful. Three months in and my digestive symptoms are much calmer.
7 months ago
Simple, clean formula. No fillers, mixes well in water. I stack it with a probiotic in the morning and it sits fine alongside everything else.
7 months ago
Doctor suggested I look into gut lining support after a long course of antibiotics for a skin infection. This was the one my pharmacist and doctor both knew about. Been using it for two months now and my digestion feels far more settled than it did before.
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