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Glucosamine is an amino sugar that serves as a building block for cartilage, while chondroitin sulphate is a glycosaminoglycan that helps cartilage retain water and resist compression.
£35
Glucosamine is an amino sugar that serves as a building block for cartilage, while chondroitin sulphate is a glycosaminoglycan that helps cartilage retain water and resist compression.
Glucosamine is an amino sugar that serves as a building block for cartilage, while chondroitin sulphate is a glycosaminoglycan that helps cartilage retain water and resist compression.
Take 3 capsules twice daily, as directed on the packaging. Consistent daily use over several weeks to months is how these compounds are typically assessed in clinical research. Taking with a meal may help with tolerability.
Thorne Glucosamine & Chondroitin is a joint-support supplement combining two of the most studied structural compounds in musculoskeletal nutrition: glucosamine sulphate and chondroitin sulphate. Glucosamine is an amino sugar that serves as a building block for cartilage, while chondroitin sulphate is a glycosaminoglycan that helps cartilage retain water and resist compression. Together, they are studied for their role in supporting joint comfort and slowing cartilage degradation, particularly in load-bearing joints such as the knees and hips.
This combination suits people experiencing early signs of joint wear, those with a diagnosis of osteoarthritis, or active individuals in prolonged high-impact training who want to support joint tissue over the long term. It is not a fast-acting analgesic - most clinical work on these compounds uses consistent daily intake over months before meaningful changes are assessed.
Thorne is a brand with a strong reputation in the practitioner community, with manufacturing standards that have made it a go-to for clinicians recommending supplements with confidence. As with any joint supplement, results vary by individual and the degree of existing joint change. Those on blood thinners should speak to their GP before starting, as chondroitin may have mild anticoagulant properties.
Standard UK delivery included on every order, 1 to 3 working days after dispatch.
Next working day for £25 when you order by 12pm. Orders placed before 12pm on a working day leave the same day. Later orders leave the next working day.
You can return unopened and unused items within 30 days of delivery. This does not affect your statutory rights. Read the delivery and returns terms
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Sign inGlucosamine and chondroitin are structural compounds, not pain relievers. Most clinical studies assess outcomes after 8 to 12 weeks of consistent use, and some research runs to six months. Do not expect rapid symptom relief — the aim is longer-term support of joint tissue.
Chondroitin sulphate may have mild anticoagulant properties, so if you are taking warfarin or any other anticoagulant medication, speak to your GP or pharmacist before starting this supplement. This is a precaution worth taking seriously.
People with diagnosed osteoarthritis, particularly of the knee or hip, and active individuals in sustained high-impact training who want to support joint tissue over time. It is not aimed at acute joint injuries, where a clinical assessment is the more appropriate first step.
The sulphate forms are the versions used in the majority of clinical research on joint health. Some products use glucosamine hydrochloride, which has a less consistent evidence base. Using sulphate forms means the formulation is more directly comparable to the compounds studied.
Glucosamine is commonly derived from shellfish. If you have a known shellfish allergy, check the product label carefully and consult your GP or allergist before taking any glucosamine-containing supplement.
Overall
6 months ago
Take these with breakfast every day without thinking about it anymore. My knees have been noticeably less stiff getting out of bed over the past couple of months. Nothing dramatic — just quieter, if that makes sense.
6 months ago
Been running half marathons for years and my hips started complaining last winter. Picked these up on a physio's suggestion. About ten weeks in and the deep ache after long runs has eased off. Still take rest days seriously but this feels like it's helping in the background.
6 months ago
Wasn't expecting much straight away — I'd read enough to know this isn't the sort of thing you feel overnight. But I'm a few weeks in now, running most days, and my knees feel noticeably less grumpy after longer sessions. Early days still, but the first impressions are good. Stacking it with magnesium in the evening.
6 months ago
Swapped from a supermarket own-brand version about four months ago. Don't know if it's brand quality or just more time on the supplement, but my knees feel better than they have in two years.
6 months ago
My GP actually suggested I try glucosamine and chondroitin before we looked at anything else. Did some research and landed on this brand for the manufacturing quality. Three months daily and I can walk down stairs without wincing. That's a win.
7 months ago
The joint support seems real — I've been consistent for about twelve weeks and my left knee is definitely less achy on long cycling days. My only gripe is the capsule size, they're on the bigger side and I have to take them with a decent amount of water or it's uncomfortable.
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