PURE Encapsulations

Nac

Pure Encapsulations NAC is a supplement providing N-Acetylcysteine, a precursor to glutathione - the body's most abundant endogenous antioxidant.

£40

1
Delivery includedArrives in 1 to 3 days30-day returns
PURE EncapsulationsNac
£401

Pure Encapsulations NAC is a supplement providing N-Acetylcysteine, a precursor to glutathione - the body's most abundant endogenous antioxidant.

Why we love it

Pure Encapsulations NAC is a supplement providing N-Acetylcysteine, a precursor to glutathione - the body's most abundant endogenous antioxidant.

  • May help maintain healthy respiratory mucus clearance
  • Suited to high training loads with elevated oxidative burden
  • Single-active formula for clean, targeted supplementation

Good to know

  • A food supplement. Do not take more than the dose on the label.
  • Not a substitute for a varied, balanced diet and a healthy lifestyle.
  • Check with your doctor first if you are pregnant, breastfeeding, taking medication or under medical care.
  • Keep out of the reach of young children.
How to use

Take 1 capsule one to two times daily, as directed on the packaging. NAC is generally better tolerated when taken with food, particularly if you have a sensitive stomach.

More about it

Pure Encapsulations NAC is a supplement providing N-Acetylcysteine, a precursor to glutathione - the body's most abundant endogenous antioxidant. By replenishing intracellular cysteine, NAC supports the ongoing production of glutathione, which plays a central role in neutralising oxidative stress and supporting detoxification pathways, particularly in the liver.

NAC is studied for its role in respiratory health, where it may help maintain normal mucus viscosity and support the mucosal lining of the airways. It is commonly considered by those with high oxidative load - including people in intensive training, individuals with regular alcohol intake, or those managing chronic inflammatory conditions. It also has a long-standing clinical history in liver support, particularly in contexts of toxic or metabolic stress.

This product suits those who have identified oxidative stress or poor antioxidant status through clinical assessment, or who are looking for targeted liver and respiratory support as part of a broader protocol. It fits naturally alongside broader antioxidant nutrition or as a standalone daily supplement.

Pure Encapsulations is a well-regarded professional supplement brand with a consistent focus on clean formulations. This product contains N-Acetylcysteine as the sole active, making it straightforward to integrate into an existing regimen without concern about overlapping nutrients from a complex blend.

Delivery and returns

Standard UK delivery included on every order, 1 to 3 working days after dispatch.

Next working day for £25 when you order by 12pm. Orders placed before 12pm on a working day leave the same day. Later orders leave the next working day.

You can return unopened and unused items within 30 days of delivery. This does not affect your statutory rights. Read the delivery and returns terms

or call 020 3951 3429

Your  Profile

Your first order creates it. Add your blood results or a wearable, and a doctor can recommend what suits you.

Sign in

Your questions

What is NAC and how does it work?

N-Acetylcysteine is a stable, bioavailable form of the amino acid cysteine. The body uses it to synthesise glutathione, a key antioxidant involved in liver detoxification and protection against oxidative damage in cells throughout the body.

Who is most likely to benefit from taking NAC?

NAC is most relevant for people with increased oxidative stress — such as those in heavy training, individuals with regular alcohol intake, or those with respiratory conditions where mucosal support is a priority. It is worth discussing with a clinician if you are unsure whether it fits your needs.

Is NAC safe to take alongside other supplements or medications?

NAC is generally well tolerated, but it can interact with certain medications, including nitroglycerin and some chemotherapy agents. If you take any prescription medication, check with your doctor or pharmacist before starting NAC.

How long before I notice a difference?

NAC works by supporting ongoing antioxidant processes rather than producing an immediate noticeable effect. Most clinical observations are made over weeks to months of consistent use, and changes may be more apparent through markers like blood glutathione levels than through subjective feeling alone.

Can I take NAC on an empty stomach?

Some people experience mild nausea when taking NAC without food. Taking it with a meal is a sensible precaution, particularly when first starting the supplement.

In their words

Overall

4.819 reflections
1 to 6 of 19 reflections
CW

Solid addition to my daily stack

6 months ago

Been taking this for about six weeks now alongside a vitamin C and magnesium. Hard to isolate what's doing what, but my chest has felt notably clearer since adding it in — I'd been getting a lot of congestion after early morning runs. Clean capsule, no filler nonsense. Worth the price for a brand I trust.

T

Does exactly what it says

6 months ago

Straightforward, no-frills supplement. That's what I want.

SO

Good quality but pricey for what you get

6 months ago

The quality is clearly there and I do feel like my energy and recovery have been a bit steadier since starting it. My only gripe is the price — £38.99 for the capsule count works out quite expensive per day compared to other NAC supplements I've seen. I'll probably keep buying it but it stings a bit.

MT

Recommended by my functional medicine GP

7 months ago

Started this as part of a liver support protocol after some elevated enzymes showed up on bloodwork. Three months in, things are looking better — obviously can't attribute it all to one supplement but this was a key part of the plan. Pure Encapsulations is consistently the brand recommended to me by practitioners, and this is no different.

PM

7 months ago

I take this before bed. Noticed my sleep feels a bit deeper, which I wasn't expecting. Mainly bought it for antioxidant support during a heavy training block. Will reorder.

JH

Swapped from a cheaper brand and noticed the difference

7 months ago

Used to take a budget NAC from a high street chain. The difference in how I feel on this is noticeable — less bloating, feels cleaner somehow. Probably the lack of fillers. Not cheap, but I'd rather spend the money here.

Pairs well with

  1. PURE Encapsulations NacPURE EncapsulationsNac£40
  2. Hunter & Gather 100% Coconut MCT OilHunter & Gather100% Coconut MCT Oil£20
Build a routine with this