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Nicotinamide riboside (NR) is a form of vitamin B3 that the body converts into nicotinamide adenine dinucleotide (NAD+), a coenzyme central to cellular energy metabolism and DNA repair.
£65
Nicotinamide riboside (NR) is a form of vitamin B3 that the body converts into nicotinamide adenine dinucleotide (NAD+), a coenzyme central to cellular energy metabolism and DNA repair.
Nicotinamide riboside (NR) is a form of vitamin B3 that the body converts into nicotinamide adenine dinucleotide (NAD+), a coenzyme central to cellular energy metabolism and DNA repair.
Take 1 capsule twice daily, or as directed by your healthcare practitioner. NR is generally well tolerated with or without food. Many people take it in the morning to align with daytime energy metabolism.
Thorne NiaCel 400 is a nicotinamide riboside supplement, delivering 400 mg of this NAD+ precursor per serving. Nicotinamide riboside (NR) is a form of vitamin B3 that the body converts into nicotinamide adenine dinucleotide (NAD+), a coenzyme central to cellular energy metabolism and DNA repair. NAD+ levels decline with age, and this decline is associated with reduced mitochondrial function and slower cellular recovery. NR is studied as one of the more bioavailable routes to raising NAD+ compared to standard niacin.
This supplement suits people who are actively monitoring their metabolic health, those in demanding physical training, or anyone whose blood work or clinical assessment has flagged concerns around energy metabolism and cellular ageing. It fits naturally into a morning routine alongside other foundational nutrition support.
Thorne is a brand with a long-standing reputation for rigorous quality standards in supplement manufacturing. NiaCel 400 uses a well-characterised form of nicotinamide riboside at a dose consistent with the amounts used in human research. For those working with a clinician to address age-related metabolic decline or optimising cellular resilience, this is a considered, evidence-informed choice rather than a speculative one.
Standard UK delivery included on every order, 1 to 3 working days after dispatch.
Next working day for £25 when you order by 12pm. Orders placed before 12pm on a working day leave the same day. Later orders leave the next working day.
You can return unopened and unused items within 30 days of delivery. This does not affect your statutory rights. Read the delivery and returns terms
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Sign inNicotinamide riboside is a form of vitamin B3 that converts to NAD+ via a distinct metabolic pathway. Unlike standard niacin, it does not typically cause the skin flushing that many people find uncomfortable, making it easier to take consistently.
Human studies on NR generally run over several weeks before measuring outcomes. Most people would not expect to notice a pronounced subjective effect quickly — NAD+ support works at a cellular level rather than producing an immediate sensation. Allow at least four to eight weeks before assessing impact.
People who are pregnant, breastfeeding, or taking medications that affect NAD+ metabolism or liver function should consult a clinician before starting. As with any B3-related compound, those with liver conditions warrant medical supervision.
NR is generally considered low-risk alongside standard supplements, but if you are taking chemotherapy agents, resveratrol at high doses, or medications processed by the liver, speak to your doctor first. Check the packaging and consult your prescriber if in doubt.
Check the packaging for storage instructions specific to this product. As a general principle, NAD+ precursors are best stored away from heat, moisture, and direct light to preserve stability.
Overall
6 months ago
Been taking this for about three months now, mainly on my GP's suggestion after some blood work raised questions about my metabolic health. Hard to pin down exactly what's changed, but I feel more consistently alert through the afternoon — which used to be my worst slump. No side effects, no weird taste. Just quietly does its thing.
6 months ago
Take this alongside magnesium and a B-complex first thing. Noticed after about six weeks that my recovery between sessions felt a bit smoother — I'm in heavy training ahead of a spring marathon. Can't attribute it to one thing but this stays in the rotation.
6 months ago
No complaints about how it works — I've been on it for two months and my energy feels more stable. Only gripe is the capsules are quite large. I take a few other supplements and this one's the trickiest to swallow. Results-wise, happy enough to reorder.
6 months ago
My doctor flagged declining NAD+ as something worth addressing given my age (early 50s). She specifically suggested this brand and this product. Three months in and I feel sharper, sleep feels more restorative. Early days still but I'm encouraged.
7 months ago
7 months ago
Tried a cheaper brand before and wasn't confident in the quality. Switched here after reading about their manufacturing standards. It's pricier but I'm not cutting corners on something I'm taking daily for cellular health. Three months in and feel good about it.
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