Thorne

NiaCel 400

£60.00

Thorne NiaCel 400 is a nicotinamide riboside supplement, delivering 400 mg of this NAD+ precursor per serving.

  • Raises NAD+ levels to support cellular energy metabolism
  • May support mitochondrial function in ageing adults
  • Studied form of vitamin B3 with good bioavailability
  • Relevant for those managing age-related metabolic decline
  • Suits high-output athletes monitoring cellular recovery
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ThorneNiaCel 400
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About This Product.

Thorne NiaCel 400 is a nicotinamide riboside supplement, delivering 400 mg of this NAD+ precursor per serving. Nicotinamide riboside (NR) is a form of vitamin B3 that the body converts into nicotinamide adenine dinucleotide (NAD+), a coenzyme central to cellular energy metabolism and DNA repair. NAD+ levels decline with age, and this decline is associated with reduced mitochondrial function and slower cellular recovery. NR is studied as one of the more bioavailable routes to raising NAD+ compared to standard niacin.

This supplement suits people who are actively monitoring their metabolic health, those in demanding physical training, or anyone whose blood work or clinical assessment has flagged concerns around energy metabolism and cellular ageing. It fits naturally into a morning routine alongside other foundational nutrition support.

Thorne is a brand with a long-standing reputation for rigorous quality standards in supplement manufacturing. NiaCel 400 uses a well-characterised form of nicotinamide riboside at a dose consistent with the amounts used in human research. For those working with a clinician to address age-related metabolic decline or optimising cellular resilience, this is a considered, evidence-informed choice rather than a speculative one.

Nicotinamide Riboside 400mg

NiaCel 400

How to Take It

i.

Take 1 capsule twice daily, or as directed by your healthcare practitioner. NR is generally well tolerated with or without food. Many people take it in the morning to align with daytime energy metabolism.

Frequently Asked.

What is nicotinamide riboside and how does it differ from regular niacin?

Nicotinamide riboside is a form of vitamin B3 that converts to NAD+ via a distinct metabolic pathway. Unlike standard niacin, it does not typically cause the skin flushing that many people find uncomfortable, making it easier to take consistently.

How long before I notice a difference?

Human studies on NR generally run over several weeks before measuring outcomes. Most people would not expect to notice a pronounced subjective effect quickly — NAD+ support works at a cellular level rather than producing an immediate sensation. Allow at least four to eight weeks before assessing impact.

Who should avoid this supplement?

People who are pregnant, breastfeeding, or taking medications that affect NAD+ metabolism or liver function should consult a clinician before starting. As with any B3-related compound, those with liver conditions warrant medical supervision.

Can I take NiaCel 400 alongside other supplements or medications?

NR is generally considered low-risk alongside standard supplements, but if you are taking chemotherapy agents, resveratrol at high doses, or medications processed by the liver, speak to your doctor first. Check the packaging and consult your prescriber if in doubt.

Does this need to be refrigerated?

Check the packaging for storage instructions specific to this product. As a general principle, NAD+ precursors are best stored away from heat, moisture, and direct light to preserve stability.

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Customer Reflections

Overall Sentiment

4.927 reflections
1 – 6 of 27 reflections
SK

Steady energy, no jitters

4 months ago

Been taking this for about three months now, mainly on my GP's suggestion after some blood work raised questions about my metabolic health. Hard to pin down exactly what's changed, but I feel more consistently alert through the afternoon — which used to be my worst slump. No side effects, no weird taste. Just quietly does its thing.

MT

Solid addition to my morning stack

4 months ago

Take this alongside magnesium and a B-complex first thing. Noticed after about six weeks that my recovery between sessions felt a bit smoother — I'm in heavy training ahead of a spring marathon. Can't attribute it to one thing but this stays in the rotation.

FD

Good product, capsule size is a bit much

5 months ago

No complaints about how it works — I've been on it for two months and my energy feels more stable. Only gripe is the capsules are quite large. I take a few other supplements and this one's the trickiest to swallow. Results-wise, happy enough to reorder.

O

Recommended by my functional medicine doctor

5 months ago

My doctor flagged declining NAD+ as something worth addressing given my age (early 50s). She specifically suggested this brand and this product. Three months in and I feel sharper, sleep feels more restorative. Early days still but I'm encouraged.

JW

5 months ago

PM

Finally a NR supplement I trust

5 months ago

Tried a cheaper brand before and wasn't confident in the quality. Switched here after reading about their manufacturing standards. It's pricier but I'm not cutting corners on something I'm taking daily for cellular health. Three months in and feel good about it.

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