Niacinamide

Name: Niacinamide
Brand: Pure Encapsulations
SKU: product-0263
Price: 30.00 GBP
Availability: InStock
Rating: 4.9 (28 reviews)

£30.00

Niacinamide is a form of vitamin B3 — specifically the amide form of nicotinic acid — that plays a central role in cellular energy metabolism.

Supports cellular energy via NAD+ coenzyme pathways
May help maintain healthy skin barrier function
Better-tolerated B3 form — no flushing response
Studied for cardiovascular and cholesterol metabolism support
Minimal-excipient formula suited to sensitive individuals

4.9 (28 reflections)

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About This Product.

Niacinamide is a form of vitamin B3 — specifically the amide form of nicotinic acid — that plays a central role in cellular energy metabolism. It is a precursor to NAD+ and NADH, coenzymes involved in hundreds of oxidation-reduction reactions across the body, from ATP production to DNA repair. Unlike nicotinic acid, niacinamide does not typically cause the flushing response, making it better tolerated for daily supplementation.

This supplement suits a broad range of people. Those managing fatigue, supporting skin barrier function, or looking to maintain healthy cholesterol metabolism within normal ranges may find niacinamide a useful addition to their routine. It is also studied for its role in supporting cognitive function and has attracted interest in longevity research for its connection to NAD+ pathways. It fits well alongside a B-complex or as a standalone when a specific B3 focus is warranted — for example, where a clinician has identified suboptimal B3 intake through dietary review.

Pure Encapsulations is a brand with a reputation for clean, minimal-excipient formulations, consistently favoured in clinical settings where patients have sensitivities to fillers or additives. The single active-ingredient approach here makes dosing straightforward and allows precise titration under professional guidance. As always with B-vitamin supplementation, context matters — a blood panel is the most reliable way to identify genuine need.

Frequently Asked.

What is the difference between niacinamide and niacin?

Both are forms of vitamin B3, but niacin (nicotinic acid) commonly causes a flushing sensation — redness and warmth in the skin — due to its vasodilatory effect. Niacinamide does not produce this response, making it the preferred form for daily supplementation in most people.

Who is most likely to benefit from niacinamide supplementation?

Those with suboptimal dietary B3 intake, individuals interested in NAD+ support for energy and cellular repair, and people seeking a clean, well-tolerated B-vitamin option. If you are unsure whether your B3 levels need addressing, a baseline blood panel is the most useful starting point.

Is niacinamide safe to take alongside other B vitamins or a multivitamin?

Generally yes, but it is worth checking the total B3 content across all supplements you are taking to avoid unnecessary excess. If you are already taking a B-complex or multivitamin containing niacin or niacinamide, speak to a clinician before adding a standalone dose.

How long before I notice any difference?

B-vitamin effects on energy and general wellbeing are typically gradual. Most people would not expect noticeable changes in under four to six weeks of consistent use, and outcomes vary considerably depending on baseline status.

Is this suitable for vegetarians or vegans?

Check the packaging for capsule composition and excipient details specific to this product, as shell materials can vary. Pure Encapsulations does offer many vegetarian-capsule formulations, but we recommend confirming on the label rather than assuming.

Customer Reflections

Overall Sentiment

4.928 reflections

1 – 6 of 28 reflections

Noticed a real difference in my energy levels

4 months ago

Been taking this for about six weeks now, initially on my GP's suggestion after a diet review flagged low B3 intake. Hard to isolate one supplement when you're taking a few things, but I do feel steadier energy through the afternoon — that 3pm slump has eased up noticeably. Clean formula, no fillers, which matters to me.

Good quality, no faff

4 months ago

Straightforward supplement, does what it says. Switched to this from a B-complex because my nutritionist wanted to focus specifically on B3. No side effects, easy to swallow.

Solid product but the capsule count could be better

5 months ago

Really happy with the quality — no fillers, no nonsense, and it sits well in my stack alongside magnesium and vitamin D. My only gripe is that for £27.99 you don't get a huge number of capsules, so the cost per day adds up if you're dosing twice daily. Would still buy again, just wish the value was a bit stronger.

No flush — finally

5 months ago

Tried a different brand's B3 years ago and got an awful flushing reaction. This one is completely fine — taken it daily for two months with zero issues. Skin has been looking clearer too, though I can't say for certain that's the cause.

5 months ago

Take it with breakfast every day. Noticed my skin feels more settled, especially around dry patches I've had for ages. Didn't expect much from a supplement tbh but pleasantly surprised.

Recommended by my integrative doctor

5 months ago

My doctor flagged suboptimal B3 on a blood panel and pointed me towards this specific brand for the clean formula. Three months in and I feel like my baseline energy is more consistent. Would trust this brand again.

Niacinamide

About This Product.

How to Take It

Frequently Asked.

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