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Take 2 softgels twice daily, as stated on the packaging. Take with a meal containing fat to support absorption of both omega-3 fatty acids and CoQ10, which are fat-soluble nutrients.
Thorne Omega-3 with CoQ10 combines two well-studied nutritional compounds in a single softgel formula. The omega-3 fatty acids EPA and DHA are the marine-derived long-chain fats most associated with cardiovascular and inflammatory support. CoQ10 (ubiquinone) is a fat-soluble compound central to mitochondrial energy production and studied for its role in protecting cells from oxidative stress - a function that aligns naturally with the lipid environment omega-3s occupy in the body.
This combination suits people managing cardiovascular risk factors, those on statin therapy (statins are associated with reduced endogenous CoQ10 synthesis), adults in their 40s and beyond whose CoQ10 levels tend to decline with age, and anyone seeking consolidated supplementation rather than multiple separate capsules.
Both ingredients are fat-soluble, so taking them together with a meal supports absorption. Thorne is a brand with a strong clinical reputation - it is used directly by healthcare practitioners and holds itself to formulation standards that have made it a common choice in functional medicine settings. As with any omega-3 supplement, those on anticoagulant medication should discuss use with their prescribing clinician before starting, as high-dose fish oil may affect bleeding time.
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Next working day for £25 when you order by 12pm. Orders placed before 12pm on a working day leave the same day. Later orders leave the next working day.
You can return unopened and unused items within 30 days of delivery. This does not affect your statutory rights. Read the delivery and returns terms
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Sign inBoth nutrients are fat-soluble, which means they absorb well in the same lipid environment and pair logically in a single softgel. It also reduces the number of separate supplements you need to take.
Statins inhibit the mevalonate pathway, which the body uses to synthesise CoQ10 as well as cholesterol. Many clinicians recommend CoQ10 supplementation alongside statin therapy, though you should discuss this with your prescribing doctor before adding any supplement.
Omega-3 and CoQ10 are not fast-acting compounds — most research looks at outcomes over weeks to months of consistent use. A baseline blood test can help track relevant markers such as triglycerides over time.
High-dose omega-3 supplementation may have an additive effect on bleeding time when taken alongside anticoagulants such as warfarin or apixaban. Speak with your prescribing clinician before starting if you are on any anticoagulant or antiplatelet therapy.
It is better taken with a meal. Both EPA/DHA and CoQ10 are fat-soluble and absorb more effectively when dietary fat is present. Taking them on an empty stomach may also cause mild digestive discomfort in some people.
Overall
6 months ago
Take one of these with breakfast every day. Started about four months ago after my GP mentioned CoQ10 alongside the statin I was prescribed. Energy feels steadier in the afternoons and I don't have to remember two separate capsules. Good quality, no fishy repeat.
6 months ago
Wasn't expecting to notice anything quickly — most supplements take months to feel different. But by the end of the first week I genuinely felt less heavy-legged after my morning runs. I'd been taking CoQ10 and fish oil separately for ages, so consolidating them into one softgel was the main draw. First impressions: easy to swallow, no fishy aftertaste at all (which was my biggest worry), and they sit fine with breakfast. Early days still but off to a solid start.
6 months ago
I was taking omega-3 and CoQ10 separately before and the consolidation alone was worth the switch. These sit well on the stomach even on an empty morning — though I try to take them with food as recommended.
6 months ago
My main gripe with fish oil supplements has always been the aftertaste. These don't have that problem at all. Been using them for about six weeks alongside my usual morning vitamins. Feels like a quality product.
6 months ago
Quality seems very good and I like the convenience of having omega-3 and CoQ10 in one capsule. My only gripe is the price — £44.99 for the bottle feels steep when you compare it to buying them separately on a budget. That said, I trust this brand more than the cheap alternatives so I'll keep buying.
7 months ago
My cardiologist suggested CoQ10 support given my medication. Chose this because it combines both in one capsule. Easy to swallow, no issues. Been on it for about ten weeks now.
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