Thorne

Thorne Vitamin K

£30.00

The most comprehensive vitamin K supplement available — combining K1, K2 as MK-4 (5 mg), and K2 as MK-7 (MenaQ7, 90 mcg) in a single capsule that covers coagulation, bone mineralisation, and arterial calcium regulation…

  • Vitamin K2 as MK-4 at 5 mg is the form most concentrated in human bone, brain, pancreas, and vascular tissue — it activates osteocalcin for calcium incorporation into bone and matrix Gla protein for prevention of arterial calcification, at a dose substantially higher than most consumer K2 supplements provide
  • Vitamin K2 as MK-7 (MenaQ7) at 90 mcg is the most extensively researched long-acting K2 form, with a biological half-life of approximately 72 hours — maintaining activated K-dependent proteins between doses and providing published clinical evidence for improvements in bone mineral density and arterial flexibility
  • Vitamin K1 at 1 mg supplies the primary substrate for hepatic synthesis of coagulation factors II, VII, IX, and X — the proteins that form the clotting cascade activated in response to vascular injury
  • The triple-form combination provides both rapid tissue-level activity (MK-4 peaks within hours), sustained systemic coverage (MK-7 maintains activity for days), and coagulation support (K1) — a comprehensive approach that single-form supplements structurally cannot achieve
  • Vitamin K contributes to the maintenance of normal bones and normal blood clotting
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about this product.

The most comprehensive vitamin K supplement available — combining K1, K2 as MK-4 (5 mg), and K2 as MK-7 (MenaQ7, 90 mcg) in a single capsule that covers coagulation, bone mineralisation, and arterial calcium regulation through three distinct forms working across different tissue types and timeframes.

Vitamin K is the nutrient almost nobody thinks about and almost everybody needs more of. It is essential for two processes your body cannot function safely without: blood clotting and calcium trafficking. Without adequate K1, your blood cannot coagulate properly — cuts bleed longer, bruises form more easily, and internal bleeding risk increases. Without adequate K2, the calcium your body absorbs from food and vitamin D supplementation has no direction — it may deposit in bone matrix where it strengthens your skeleton, or it may accumulate in arterial walls where it stiffens blood vessels and accelerates cardiovascular disease. The difference between these two outcomes is determined almost entirely by whether enough activated vitamin K-dependent proteins are present to route calcium correctly.

Most people supplementing vitamin D without K2 are increasing calcium absorption without ensuring it reaches the right destination. The vitamin K market is fragmented and confusing. K1 supplements support coagulation but do not meaningfully activate the bone and vascular proteins that K2 governs. MK-7 supplements provide long-acting K2 with a 72-hour half-life but at doses too low to match the tissue-level activity of MK-4. MK-4 supplements deliver the form most concentrated in bone, brain, and reproductive tissue but clear the bloodstream within hours, requiring higher doses or multiple daily servings.

Most products contain one form at one dose and call it complete. You buy K1 for clotting, or MK-7 for convenience, or MK-4 for potency — and whichever you choose, the other pathways remain unsupported.

Thorne Vitamin K eliminates the compromise by combining all three forms in a single capsule at clinically meaningful doses. Vitamin K1 (1 mg) provides the substrate for hepatic production of clotting factors II, VII, IX, and X — the coagulation cascade your body activates every time tissue is damaged. Vitamin K2 as MK-4 (5 mg) is the form most concentrated in human tissue — particularly bone, brain, pancreas, and arteries — where it activates osteocalcin (directing calcium into bone) and matrix Gla protein (preventing calcium deposition in blood vessels). At 5 mg, this is a substantially higher MK-4 dose than most competitors offer. Vitamin K2 as MK-7 (90 mcg as MenaQ7) provides the long-acting form with a 72-hour half-life that maintains baseline K2 activity between doses — MenaQ7 is the most clinically validated MK-7 on the market, with published research on bone density and arterial flexibility. The three forms together create continuous, multi-tissue vitamin K coverage that no single form can achieve.

Thorne is NSF Certified for Sport, third-party tested through four rounds of quality verification. No gluten, dairy, soy, artificial colours, or preservatives. 60 capsules per bottle — a one-to-two-month supply.

Vitamin K2 (as MK-4 / Menatetrenone) 5 mg, Vitamin K1 (Phytonadione) 1 mg, Vitamin K2 (as MK-7 / MenaQ7) 90 mcg, Bulking Agent (Microcrystalline Cellulose), Hypromellose Capsule (Derived from Cellulose), Anti-Caking Agent (Silicon Dioxide), Antioxidant (Vitamin E as Mixed Tocopherols)

how to take it

i.

Take one capsule one to two times daily, or as recommended by your healthcare professional. Can be taken with or without food, though a meal containing dietary fat may enhance absorption. Best paired with vitamin D3 supplementation — vitamin D increases calcium absorption, and vitamin K directs that calcium to bone rather than arterial tissue. Do not use if taking anticoagulant medications (warfarin, acenocoumarol, phenprocoumon) — vitamin K directly opposes the mechanism of these drugs and will reduce their effectiveness. If you are on any anticoagulant therapy, consult your prescribing doctor before supplementing. If pregnant, consult your healthcare professional before use. Store in a cool, dry place. Keep out of reach of children. 60 capsules per bottle.

ii.

Three forms, one capsule, complete calcium logic — because the vitamin that decides where calcium goes deserves as much attention as the vitamin that puts it there.

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Customer reflections

Overall sentiment

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QQVerified Buyer

The first adrenal support that made a quick difference.

4 days ago

Gentle on a sensitive stomach, and I feel like myself again. I had tried two other glandulars before this and neither sat right.

MRVerified Buyer

Steadier mornings within a fortnight.

1 week ago

I was sceptical about glandulars, but my mid-afternoon crash has genuinely eased. One capsule with breakfast and I forget about it.

ALVerified Buyer

Subtle, but real.

2 weeks ago

Not a stimulant, which is exactly what I wanted. It took about ten days, then I realised I wasn’t dreading the afternoon any more.

SKVerified Buyer

My clinician recommended it.

3 weeks ago

Bought after a blood panel flagged a flat cortisol curve. Easy to take, no jitters, and the sourcing is refreshingly transparent.

TPVerified Buyer

Recovery feels faster.

1 month ago

Training hard through a stressful stretch and this has helped me bounce back between sessions. Already on my second bottle.

DVVerified Buyer

Does what it says.

1 month ago

No frills, one ingredient, a sensible dose. I appreciate that it is designed to be used for a season rather than forever.

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