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Curated, not stocked.
We include Tru Niagen because nicotinamide riboside is the NAD+ precursor with the most substantial body of peer-reviewed human clinical evidence behind it. In a market crowded with poorly studied longevity supplements, that distinction matters. It is the product our clinicians reach for when a patient wants to address age-related NAD+ decline with something more than preclinical promise.
About this product
Tru Niagen NAD+ 300mg
Tru Niagen is a nicotinamide riboside (NR) supplement designed to support NAD+ levels in the body. NAD+ — nicotinamide adenine dinucleotide — is a coenzyme found in every cell, where it plays a central role in energy metabolism and DNA repair. Levels decline naturally with age, and that decline is studied in the context of fatigue, cognitive sluggishness, and reduced cellular resilience. Nicotinamide riboside is one of the best-researched NAD+ precursors available; unlike direct NAD+ supplementation, NR is efficiently absorbed and converted into NAD+ within cells.
This supplement suits those in their late thirties and beyond who want to address age-related NAD+ decline, as well as individuals managing high physical or cognitive loads who feel their recovery and energy are no longer what they were. It fits neatly into a morning routine alongside other foundational supplements.
Tru Niagen is the branded NR ingredient with a notable body of human clinical research behind it — a meaningful distinction in a category where many products rely on preclinical data alone. If you are considering an NAD+ precursor and want a formulation backed by peer-reviewed human trials, this is a considered starting point. As with any supplement affecting cellular metabolism, those on medications or with existing health conditions should speak to a clinician before starting.
What it does
Benefits
- 01
Supports NAD+ levels that naturally decline with age
- 02
May aid cellular energy production and metabolic function
- 03
Studied for recovery support in periods of high physical demand
- 04
Nicotinamide riboside: an efficiently absorbed NAD+ precursor
- 05
Backed by peer-reviewed human clinical research on NR
Get the most from it
How to use
Follow the dosage on the packaging. Tru Niagen is typically taken once daily, and most people find it easiest to take in the morning with or without food. Check the label for the specific serving size recommended by the manufacturer.
What's inside
Ingredients
View full ingredient list
NAD+ booster for cellular health
Common questions
Frequently asked
What is nicotinamide riboside and how does it differ from NAD+ itself?
Nicotinamide riboside (NR) is a form of vitamin B3 that the body converts into NAD+ intracellularly. Taking NAD+ directly is not an efficient route — the molecule does not cross cell membranes readily. NR is absorbed and then synthesised into NAD+ inside the cell, which is why it is the preferred delivery form in most clinical research.
How long before I might notice a difference?
Human studies on NR typically measure NAD+ blood levels after two to four weeks of consistent use. Subjective changes — in energy or recovery — may take longer and are not guaranteed. NAD+ precursors are better thought of as foundational support than as fast-acting interventions.
Is this safe to take alongside other supplements or medications?
NR is generally well tolerated, but if you are taking any prescription medications — particularly those affecting metabolism or cancer treatment — speak to your GP or a clinician before starting. This is standard advice for any supplement that influences cellular biochemistry.
Who is this particularly suited to?
It is most relevant for adults in their late thirties and older who are interested in addressing age-related NAD+ decline, as well as those experiencing persistent fatigue or reduced recovery that blood tests have not attributed to a specific deficiency. It is not a substitute for investigating underlying causes with a clinician.
Does the 300mg on the label refer to NAD+ content?
The 300mg refers to the dose of nicotinamide riboside (NR), the precursor — not to NAD+ itself. Check the product packaging for the full supplement facts panel and any additional ingredients included in the formulation.
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