Vitamin D 10,000

Name: Vitamin D 10,000
Brand: Thorne
SKU: product-0547
Price: 20.00 GBP
Availability: InStock
Rating: 4.9 (34 reviews)

£20.00

Thorne Vitamin D 10,000 is a high-potency vitamin D3 supplement, providing 10,000 IU of cholecalciferol per capsule.

Supports bone mineralisation and calcium absorption
May correct confirmed vitamin D deficiency or insufficiency
Suited to individuals with limited sun exposure or poor absorption
Contributes to normal immune system function
Single-ingredient, clearly dosed cholecalciferol (D3)

4.9 (34 reflections)

One-time purchase£20.00

ThorneVitamin D 10,000

Interested in more
personalised recommendations?

Set up your WA\ Profile to connect your wearables, biomarkers and test results. Create a bespoke plan based on your unique biology. Expert-led, evidence-based.

Set up Profile now

about this product.

Thorne Vitamin D 10,000 is a high-potency vitamin D3 supplement, providing 10,000 IU of cholecalciferol per capsule. Cholecalciferol is the form the body produces in response to sunlight and the form most readily converted to the active hormone, calcitriol. At this dose, it is not a maintenance supplement for the general population — it is intended for individuals with confirmed deficiency or insufficiency, typically identified through a 25-hydroxyvitamin D blood test.

Vitamin D3 at this level is studied for supporting bone mineralisation by improving calcium and phosphate absorption, for modulating immune function, and for correcting the fatigue and low mood that can accompany significant deficiency. It suits people with very low baseline levels, those with limited sun exposure, individuals with higher bodyweight (where distribution volume is larger), or those with absorption conditions that impair fat-soluble vitamin uptake.

Because vitamin D is fat-soluble and accumulates in tissue, regular monitoring via blood test is sensible at this dose — over-supplementation carries a genuine risk of toxicity. Thorne is a brand with a strong reputation in the clinical supplement space, known for rigorous manufacturing standards and minimal excipients. This formulation delivers a single, clearly dosed active ingredient with no unnecessary fillers, which is consistent with their wider range.

how to take it

Take 1 capsule daily with a meal containing fat, as vitamin D3 is fat-soluble and absorption is improved in the presence of dietary fat. Do not exceed the stated dose without guidance from a clinician. If you are taking a high-potency dose long-term, periodic blood testing to monitor your 25-hydroxyvitamin D level is advisable.

frequently asked.

Do I need a blood test before taking this dose?

At 10,000 IU, a blood test is strongly advisable. This dose is intended for confirmed deficiency, not general maintenance. Your clinician can interpret your 25-hydroxyvitamin D result and advise whether this level is appropriate for you.

Is it safe to take vitamin D3 at this dose long-term?

Vitamin D is fat-soluble and accumulates in the body, so long-term use at high doses carries a risk of toxicity if levels are not monitored. Periodic blood testing allows your dose to be adjusted once levels are restored. Follow your clinician's guidance on duration.

Why D3 rather than D2?

Cholecalciferol (D3) is the form the body synthesises naturally and is generally considered more effective at raising and sustaining blood levels of 25-hydroxyvitamin D compared to ergocalciferol (D2).

Should I take this with food?

Yes. Vitamin D3 is a fat-soluble vitamin, so taking it with a meal that contains some fat improves absorption. Avoid taking it on an empty stomach.

Who should avoid this supplement?

People with hypercalcaemia, sarcoidosis, certain lymphomas, or primary hyperparathyroidism should avoid high-dose vitamin D without specialist supervision. Those on certain medications, including thiazide diuretics or digoxin, should consult their doctor before use.

Customer reflections

Overall sentiment

4.934 reflections

1 – 6 of 34 reflections

QQVerified Buyer

The first adrenal support that made a quick difference.

4 days ago

Gentle on a sensitive stomach, and I feel like myself again. I had tried two other glandulars before this and neither sat right.

MRVerified Buyer

Steadier mornings within a fortnight.

1 week ago

I was sceptical about glandulars, but my mid-afternoon crash has genuinely eased. One capsule with breakfast and I forget about it.

ALVerified Buyer

Subtle, but real.

2 weeks ago

Not a stimulant, which is exactly what I wanted. It took about ten days, then I realised I wasn’t dreading the afternoon any more.

SKVerified Buyer

My clinician recommended it.

3 weeks ago

Bought after a blood panel flagged a flat cortisol curve. Easy to take, no jitters, and the sourcing is refreshingly transparent.

TPVerified Buyer

Recovery feels faster.

1 month ago

Training hard through a stressful stretch and this has helped me bounce back between sessions. Already on my second bottle.

DVVerified Buyer

Does what it says.

1 month ago

No frills, one ingredient, a sensible dose. I appreciate that it is designed to be used for a season rather than forever.

Vitamin D 10,000

about this product.

how to take it

frequently asked.

you may also like

AEKE B1 Fitness Bench

AEKE K1 AI-Powered Smart Home Gym

Dryft Sleep Mouth Tape Sleep Strips

Frenz Brainband Sleep Wearable

Finding your calm in a stressful environment

Customer reflections