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Thorne Vitamin D 10,000 is a high-potency vitamin D3 supplement, providing 10,000 IU of cholecalciferol per capsule.
£20
Thorne Vitamin D 10,000 is a high-potency vitamin D3 supplement, providing 10,000 IU of cholecalciferol per capsule.
Thorne Vitamin D 10,000 is a high-potency vitamin D3 supplement, providing 10,000 IU of cholecalciferol per capsule. Cholecalciferol is the form the body produces in response to sunlight and the form most readily converted to the active hormone, calcitriol.
Take 1 capsule daily with a meal containing fat, as vitamin D3 is fat-soluble and absorption is improved in the presence of dietary fat. Do not exceed the stated dose without guidance from a clinician. If you are taking a high-potency dose long-term, periodic blood testing to monitor your 25-hydroxyvitamin D level is advisable.
Thorne Vitamin D 10,000 is a high-potency vitamin D3 supplement, providing 10,000 IU of cholecalciferol per capsule. Cholecalciferol is the form the body produces in response to sunlight and the form most readily converted to the active hormone, calcitriol. At this dose, it is not a maintenance supplement for the general population - it is intended for individuals with confirmed deficiency or insufficiency, typically identified through a 25-hydroxyvitamin D blood test.
Vitamin D3 at this level is studied for supporting bone mineralisation by improving calcium and phosphate absorption, for modulating immune function, and for correcting the fatigue and low mood that can accompany significant deficiency. It suits people with very low baseline levels, those with limited sun exposure, individuals with higher bodyweight (where distribution volume is larger), or those with absorption conditions that impair fat-soluble vitamin uptake.
Because vitamin D is fat-soluble and accumulates in tissue, regular monitoring via blood test is sensible at this dose - over-supplementation carries a genuine risk of toxicity. Thorne is a brand with a strong reputation in the clinical supplement space, known for rigorous manufacturing standards and minimal excipients. This formulation delivers a single, clearly dosed active ingredient with no unnecessary fillers, which is consistent with their wider range.
Standard UK delivery included on every order, 1 to 3 working days after dispatch.
Next working day for £25 when you order by 12pm. Orders placed before 12pm on a working day leave the same day. Later orders leave the next working day.
You can return unopened and unused items within 30 days of delivery. This does not affect your statutory rights. Read the delivery and returns terms
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Sign inAt 10,000 IU, a blood test is strongly advisable. This dose is intended for confirmed deficiency, not general maintenance. Your clinician can interpret your 25-hydroxyvitamin D result and advise whether this level is appropriate for you.
Vitamin D is fat-soluble and accumulates in the body, so long-term use at high doses carries a risk of toxicity if levels are not monitored. Periodic blood testing allows your dose to be adjusted once levels are restored. Follow your clinician's guidance on duration.
Cholecalciferol (D3) is the form the body synthesises naturally and is generally considered more effective at raising and sustaining blood levels of 25-hydroxyvitamin D compared to ergocalciferol (D2).
Yes. Vitamin D3 is a fat-soluble vitamin, so taking it with a meal that contains some fat improves absorption. Avoid taking it on an empty stomach.
People with hypercalcaemia, sarcoidosis, certain lymphomas, or primary hyperparathyroidism should avoid high-dose vitamin D without specialist supervision. Those on certain medications, including thiazide diuretics or digoxin, should consult their doctor before use.
Overall
6 months ago
Had a blood test last autumn showing I was severely deficient — GP suggested a high-dose supplement alongside diet changes. Been on these for about three months and my follow-up test showed a significant improvement. Clean capsule, easy to swallow, no fillers that upset my stomach. Take it with my main meal of the day.
6 months ago
Exactly what it says — high dose D3, nothing extra. My naturopath recommended this brand specifically because of the clean formulation. Three months in and my fatigue has notably improved. Hard to attribute it to one thing but my bloods look much better.
6 months ago
Confirmed deficiency via blood test, GP said to supplement aggressively. These are well made, easy to take, and my levels are heading in the right direction.
6 months ago
Really pleased with the quality and I've noticed a genuine improvement in energy levels over the past couple of months. Only gripe is the capsule is a bit larger than I expected — nothing deal-breaking, just slightly awkward to swallow. Would still recommend, especially if your levels are low.
7 months ago
Swapped from a cheaper supermarket brand after seeing no movement in my blood test results. Not sure if it was the dose or the quality, but levels are finally improving. Take it with breakfast and a bit of fat — seems to help absorption.
7 months ago
Winter in the UK is brutal for vitamin D. My GP flagged a significant deficiency last year and suggested a high-potency supplement. The low-grade low mood I'd been carrying around for months started to lift after about six weeks. Obviously can't pin everything on one supplement but the timing tracks.
Biomarker check, £350MaryleboneSee your vitamin D, iron and B12.At our clinic in Marylebone, London, doctors also offer private blood tests and longevity medicine.
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