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Pure Encapsulations Vitamin D3 5000 IU delivers cholecalciferol, the same form the body produces in response to sunlight and the form most readily converted to the active hormone calcitriol.
£20
Pure Encapsulations Vitamin D3 5000 IU delivers cholecalciferol, the same form the body produces in response to sunlight and the form most readily converted to the active hormone calcitriol.
Pure Encapsulations Vitamin D3 5000 IU delivers cholecalciferol, the same form the body produces in response to sunlight and the form most readily converted to the active hormone calcitriol. At 5000 IU per capsule, this is a higher-potency option designed for people with confirmed or likely deficiency rather than a general maintenance dose.
Take 1 capsule daily, or as directed by your doctor or healthcare practitioner. Taking it with a meal containing fat may support absorption, as vitamin D3 is fat-soluble. At 5000 IU, this is a higher-potency dose - use alongside periodic blood monitoring where possible.
Vitamin D3 is studied for its roles in calcium absorption and bone mineralisation, immune regulation, and mood. Deficiency is common in the UK, where low sunlight exposure for much of the year means many people - particularly those who are older, darker-skinned, or spend little time outdoors - run chronically low without knowing it. A serum 25(OH)D blood test is the appropriate way to establish whether supplementation at this level is warranted.
This dose is typically used under clinical guidance: to correct a documented deficiency, to maintain adequate levels in someone whose baseline tends to drop, or during winter months when dietary and sunlight sources are insufficient. It suits adults who have been advised to supplement beyond standard low-dose options.
Pure Encapsulations is a professional-grade brand with a long-standing presence in clinical practice, known for minimal excipient formulas. This SKU contains a single active ingredient - cholecalciferol - with no unnecessary additives, making it straightforward to incorporate into an existing supplement protocol.
Standard UK delivery included on every order, 1 to 3 working days after dispatch.
Next working day for £25 when you order by 12pm. Orders placed before 12pm on a working day leave the same day. Later orders leave the next working day.
You can return unopened and unused items within 30 days of delivery. This does not affect your statutory rights. Read the delivery and returns terms
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Sign inIt is advisable, yes. At higher potencies, vitamin D can accumulate over time since it is fat-soluble. A serum 25(OH)D test tells you where your levels actually sit, which allows a clinician to recommend an appropriate dose and duration rather than guessing.
Vitamin D works gradually. If you are correcting a deficiency, meaningful improvement in levels typically takes several weeks of consistent supplementation. Symptoms like fatigue or low mood linked to deficiency may shift over a similar timeframe, though individual response varies.
Anyone with hypercalcaemia, granulomatous conditions such as sarcoidosis, or certain kidney disorders should seek medical advice before supplementing at this dose. Those taking medications that interact with vitamin D metabolism — including some anticonvulsants and certain diuretics — should also check with their prescriber.
Cholecalciferol (D3) is the form synthesised naturally in human skin and is generally considered more effective at raising and sustaining serum 25(OH)D levels compared to ergocalciferol (D2), making it the preferred form in most clinical contexts.
Possibly, but check the vitamin D content of your multivitamin first. Adding 5000 IU on top of a multivitamin that already contains a meaningful dose of D3 could result in a combined intake that exceeds what your blood levels require. A blood test removes the guesswork.
Overall
6 months ago
Was consistently low on D3 despite eating well and getting outside. GP suggested a higher dose and I landed on these. Six weeks later my levels are back in the normal range. Simple capsule, no weird fillers, easy to swallow. Will keep buying.
6 months ago
Solid product. No nonsense ingredients list, which is what I wanted.
6 months ago
The quality is clearly there — clean formula, capsules are easy to take. My only gripe is that you only get 60 capsules per bottle which means I'm reordering every two months. Would love a 120-count option at this price point.
6 months ago
My nutritionist recommended this brand specifically for the minimal excipients. Been taking it daily for about three months now and my follow-up blood test showed a solid improvement. Happy with it.
7 months ago
I always dip in autumn/winter and started these in October. Definitely notice a difference in energy and mood compared to last year. Can't say if it's entirely the D3 but the timing lines up.
7 months ago
Biomarker check, £350MaryleboneSee your vitamin D, iron and B12.At our clinic in Marylebone, London, doctors also offer private blood tests and longevity medicine.
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