Thorne

Berberine - 1000mg

£35.00

A dual-form berberine combining standard berberine HCl with phytosome-complexed berberine for enhanced absorption — 1000 mg per serving of one of the most extensively researched botanical compounds in metabolic science,…

• Berberine activates AMPK (adenosine monophosphate-activated protein kinase), the enzyme that functions as a cellular energy sensor — when activated, AMPK increases glucose uptake into cells, enhances insulin sensitivity, stimulates fatty acid oxidation, and inhibits hepatic glucose production.
• Berberine phytosome technology binds the alkaloid to phospholipids, creating a lipid-compatible complex that crosses the intestinal barrier more efficiently than free berberine HCl, delivering higher systemic concentrations at equivalent doses.
• Standard berberine HCl provides direct activity in the gut lumen — modulating the intestinal microbiome, reducing intestinal glucose absorption, and exerting local antimicrobial effects against pathogenic bacteria while supporting beneficial flora.
• The dual-form combination ensures both local gastrointestinal benefit (HCl) and systemic metabolic activation (phytosome) — a more complete mechanism of action than either form alone.
• Over 5,000 peer-reviewed studies have investigated berberine's effects on glucose metabolism, lipid profiles, inflammatory markers, gut microbiome composition, and AMPK-mediated cellular energy pathways.