New Hair Loss Pill 2026. VDPHL01 Explained
VDPHL01 is a new once-daily tablet for pattern hair loss, made by the US company Veradermics. It is an extended-release form of minoxidil, the same medicine used in hair loss foams and solutions, designed to release slowly through the day. In a trial of 519 men, it increased hair count by about 30 hairs per square centimetre at 6 months, against about 7 with placebo. It is not yet approved anywhere. Low-dose oral minoxidil, the older version of the same idea, is already prescribed off-label by experienced doctors in London.
Key points
- In the Phase 2/3 trial known as Study 302, 519 men with mild to moderate male pattern hair loss took VDPHL01 or placebo once a day. At 6 months, hair count rose by 30.3 hairs per square centimetre with VDPHL01 against 7.3 with placebo.
- 79.3 percent of men on VDPHL01 reported improved hair coverage, against 35.6 percent on placebo, and the difference from placebo was visible from month 2.
- A confirmatory men’s trial is due to report in the second half of 2026 and a women’s trial of 556 participants in the first half of 2027. No licence application has been announced.
- At The London PRP Clinic by The Wellness, a hair consultation with trichoscopy is from £150, and a course of 3 PRP sessions is from £1,215.
Want to start oral minoxidil or PRP now? Message our doctors on WhatsApp or email team@thewellnesslondon.com.
What VDPHL01 is
Minoxidil was first developed as a blood pressure tablet, and hair growth was noticed as a side effect. Topical minoxidil became one of the standard hair loss treatments, and in recent years doctors have increasingly prescribed low doses of the original tablet off-label for hair. That works well for many people, but the tablet was designed to lower blood pressure, not to treat hair.
VDPHL01 is a version built for hair. It releases minoxidil slowly over the day, which the company says gives steady exposure to the follicle while aiming to keep effects on blood pressure and heart rate low. It is taken once a day.
What the trials show so far
Men
Study 302 is a randomised, double-blind, placebo-controlled trial in 519 men with mild to moderate male pattern hair loss, testing an 8.5 mg dose. At 6 months, the count of thicker, non-vellus hairs in the target area rose by 30.3 per square centimetre with VDPHL01 against 7.3 with placebo, a highly significant difference. 79.3 percent of men on VDPHL01 felt their hair coverage had improved, against 35.6 percent on placebo. Full 12-month results are expected in the second half of 2026, alongside a second confirmatory trial, Study 304.
Women
An open-label Phase 2 study in women reported positive results in July 2026, with the company describing the medicine as generally well tolerated and reporting no treatment-related serious side effects and no heart-related side effects of special interest. A larger women’s trial of 556 participants is due to report in the first half of 2027.
What we do not yet know
Detailed safety data on blood pressure, heart rate, fluid retention and unwanted facial or body hair have not yet been published in full. Some headlines have claimed it beat finasteride and topical minoxidil, but the published Phase 3 data compare it with placebo. Approval would need regulators to review the full results, which usually takes time.
Want to know if oral minoxidil suits you now? Ask our doctors on WhatsApp.
When might it arrive in the UK?
No licence application has been announced in the US or the UK. If the remaining trials are positive, a US application could follow, with the UK usually later. It is unlikely to be available in UK clinics before 2028 at the earliest, and that is an estimate rather than a promise.
What you can have now
Low-dose oral minoxidil
Low-dose oral minoxidil is already prescribed off-label by doctors experienced in hair loss, after assessment of blood pressure, heart health and medicines. Side effects can include unwanted facial or body hair, ankle swelling, a faster heartbeat and light-headedness, so it needs a doctor’s assessment and follow-up. An early shed is common and usually temporary. See oral minoxidil and the minoxidil shedding phase.
PRP
PRP supports follicles with growth factors from your own blood. A 2025 meta-analysis of 43 randomised trials and 1,877 participants found it increases hair density, and a 2024 meta-analysis found higher density with PRP plus minoxidil than with minoxidil alone. See combination hair treatment.
Other options
Finasteride and its alternatives are compared in finasteride alternatives, and other treatments in development, including clascoterone and PP405, are covered in new hair loss treatments 2026.
Why waiting has a cost
Pattern hair loss is progressive, and every treatment works best on follicles that are still producing hair. Starting a proven treatment now protects the hair you have, and a new pill can be added later if it is approved.
What it costs
Flagship Harley Street and Mayfair clinics commonly charge £600 to £850 or more per PRP session.
At The London PRP Clinic by The Wellness, there are 3 ways to begin.
A hair consultation with full scalp examination and trichoscopy is from £150, included at the first session when you choose a course, and is where suitability for oral minoxidil is assessed.
A single PRP session is from £450.
A course of 3 sessions is from £1,215, as explained in PRP hair package London.
Ask what your plan would cost. Message us on WhatsApp.
Why people choose The London PRP Clinic by The Wellness
Every treatment is performed by a GMC-registered doctor, and no clinician treats a patient here until they have completed 100 supervised treatments. We follow new treatments as the evidence emerges and explain plainly what they mean for you, and every plan begins with trichoscopy and a full blood panel. We see patients at 10 Portman Square in Marylebone and the Light Centre in Belgravia. The guides for men and women are the best hair loss treatment for men and the best hair loss treatment for women.
Book your hair consultation. Message us on WhatsApp, email team@thewellnesslondon.com, or call +44 20 3951 3429.
Frequently asked questions about the new hair loss pill
What is VDPHL01?
A new once-daily extended-release minoxidil tablet for pattern hair loss, made by Veradermics. It is not yet approved anywhere.
How well does VDPHL01 work?
In a trial of 519 men, hair count rose by 30.3 hairs per square centimetre at 6 months, against 7.3 with placebo, and 79.3 percent reported improved coverage.
When will the new hair loss pill be available in the UK?
No licence application has been announced. If remaining trials are positive, UK availability is unlikely before 2028 at the earliest.
Is VDPHL01 the same as oral minoxidil?
It is the same active medicine in a new extended-release form designed for hair. Low-dose oral minoxidil is already prescribed off-label in the UK after assessment.
Does it work for women?
An early study in women reported positive results, and a larger trial of 556 women is due to report in the first half of 2027.
Should I wait for the new pill?
Pattern hair loss is progressive, so starting a proven treatment now usually protects more hair. A new pill can be considered later if it is approved.
This article is for information and does not replace personal medical advice. VDPHL01 is investigational and not approved. Oral minoxidil is a prescription medicine that needs a doctor’s assessment. All treatments at The London PRP Clinic by The Wellness are performed by GMC-registered doctors. Reviewed by a GMC-registered doctor at The London PRP Clinic by The Wellness. Last updated October 2026.
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